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Antineoplastic Effect of Decoy Oligonucleotide Derived from MGMT Enhancer

Silencing of O(6)-methylguanine-DNA-methyltransferase (MGMT) in tumors, mainly through promoter methylation, correlates with a better therapeutic response and with increased survival. Therefore, it is conceivable to consider MGMT as a potential therapeutic target for the treatment of cancers. Our pr...

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Detalles Bibliográficos
Autores principales: Canello, Tamar, Ovadia, Haim, Refael, Miri, Zrihan, Daniel, Siegal, Tali, Lavon, Iris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4252043/
https://www.ncbi.nlm.nih.gov/pubmed/25460932
http://dx.doi.org/10.1371/journal.pone.0113854