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Casein Kinase II Inhibitor Enhances Production of Infectious Genotype 1a Hepatitis C Virus (H77S)

Genotype 2a JFH1 virus has substantially contributed to the progress of HCV biology by allowing entire viral life cycle of HCV in cell culture. Using this genotype 2a virus, casein kinase II (CKII) was previously identified as a crucial host factor in virus assembly by phosphorylating NS5A. Since mo...

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Detalles Bibliográficos
Autores principales: Kim, Seungtaek, Jin, Bora, Choi, Sung Hoon, Han, Kwang-Hyub, Ahn, Sang Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4252060/
https://www.ncbi.nlm.nih.gov/pubmed/25464014
http://dx.doi.org/10.1371/journal.pone.0113938