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Decoding the Anti-Trypanosoma cruzi Action of HIV Peptidase Inhibitors Using Epimastigotes as a Model

BACKGROUND: Aspartic peptidase inhibitors have shown antimicrobial action against distinct microorganisms. Due to an increase in the occurrence of Chagas' disease/AIDS co-infection, we decided to explore the effects of HIV aspartic peptidase inhibitors (HIV-PIs) on Trypanosoma cruzi, the etiolo...

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Detalles Bibliográficos
Autores principales: Sangenito, Leandro S., Menna-Barreto, Rubem F. S., d′Avila-Levy, Claudia M., Santos, André L. S., Branquinha, Marta H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4252066/
https://www.ncbi.nlm.nih.gov/pubmed/25464510
http://dx.doi.org/10.1371/journal.pone.0113957