Distinct Roles for Hematopoietic and Extra-Hematopoietic Sphingosine Kinase-1 in Inflammatory Bowel Disease

Sphingosine kinase 1 (SK1), one of two SK enzymes, is highly regulated and has been shown to act as a focal point for the action of many growth factors and cytokines. SK1 leads to generation of sphingosine-1-phosphate (S1P) and potentially the activation of S1P receptors to mediate biologic effects....

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Detalles Bibliográficos
Autores principales: Snider, Ashley J., Ali, Wahida H., Sticca, Jonathan A., Coant, Nicolas, Ghaleb, Amr M., Kawamori, Toshihiko, Yang, Vincent W., Hannun, Yusuf A., Obeid, Lina M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4252067/
https://www.ncbi.nlm.nih.gov/pubmed/25460165
http://dx.doi.org/10.1371/journal.pone.0113998

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4252067/
https://www.ncbi.nlm.nih.gov/pubmed/25460165
http://dx.doi.org/10.1371/journal.pone.0113998

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