Specific Inhibition of the Nuclear Exporter Exportin-1 Attenuates Kidney Cancer Growth

PURPOSE: Despite the advent of FDA-approved therapeutics to a limited number of available targets (kinases and mTOR), PFS of kidney cancer (RCC) has been extended only one to two years due to the development of drug resistance. Here, we evaluate a novel therapeutic for RCC which targets the exportin...

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Detalles Bibliográficos
Autores principales: Wettersten, Hiromi I., Landesman, Yosef, Friedlander, Sharon, Shacham, Sharon, Kauffman, Michael, Weiss, Robert H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4252068/
https://www.ncbi.nlm.nih.gov/pubmed/25461627
http://dx.doi.org/10.1371/journal.pone.0113867

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4252068/
https://www.ncbi.nlm.nih.gov/pubmed/25461627
http://dx.doi.org/10.1371/journal.pone.0113867

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