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Overexpression of MEOX2 and TWIST1 Is Associated with H3K27me3 Levels and Determines Lung Cancer Chemoresistance and Prognosis

Lung cancer is the leading cause of death from malignant diseases worldwide, with the non-small cell (NSCLC) subtype accounting for the majority of cases. NSCLC is characterized by frequent genomic imbalances and copy number variations (CNVs), but the epigenetic aberrations that are associated with...

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Detalles Bibliográficos
Autores principales: Ávila-Moreno, Federico, Armas-López, Leonel, Álvarez-Moran, Aldo M., López-Bujanda, Zoila, Ortiz-Quintero, Blanca, Hidalgo-Miranda, Alfredo, Urrea-Ramírez, Francisco, Rivera-Rosales, R. María, Vázquez-Manríquez, Eugenia, Peña-Mirabal, Erika, Morales-Gómez, José, Vázquez-Minero, Juan C., Téllez-Becerra, José L., Ramírez-Mendoza, Roberto, Ávalos-Bracho, Alejandro, de Alba, Enrique Guzmán, Vázquez-Santillán, Karla, Maldonado-Lagunas, Vilma, Santillán-Doherty, Patricio, Piña-Sánchez, Patricia, Zúñiga-Ramos, Joaquin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4252097/
https://www.ncbi.nlm.nih.gov/pubmed/25460568
http://dx.doi.org/10.1371/journal.pone.0114104