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PERGA: A Paired-End Read Guided De Novo Assembler for Extending Contigs Using SVM and Look Ahead Approach

Since the read lengths of high throughput sequencing (HTS) technologies are short, de novo assembly which plays significant roles in many applications remains a great challenge. Most of the state-of-the-art approaches base on de Bruijn graph strategy and overlap-layout strategy. However, these appro...

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Detalles Bibliográficos
Autores principales: Zhu, Xiao, Leung, Henry C. M., Chin, Francis Y. L., Yiu, Siu Ming, Quan, Guangri, Liu, Bo, Wang, Yadong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4252104/
https://www.ncbi.nlm.nih.gov/pubmed/25461763
http://dx.doi.org/10.1371/journal.pone.0114253