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PERGA: A Paired-End Read Guided De Novo Assembler for Extending Contigs Using SVM and Look Ahead Approach
Since the read lengths of high throughput sequencing (HTS) technologies are short, de novo assembly which plays significant roles in many applications remains a great challenge. Most of the state-of-the-art approaches base on de Bruijn graph strategy and overlap-layout strategy. However, these appro...
Autores principales: | Zhu, Xiao, Leung, Henry C. M., Chin, Francis Y. L., Yiu, Siu Ming, Quan, Guangri, Liu, Bo, Wang, Yadong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4252104/ https://www.ncbi.nlm.nih.gov/pubmed/25461763 http://dx.doi.org/10.1371/journal.pone.0114253 |
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