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Molecular Characterization of an Intact p53 Pathway Subtype in High-Grade Serous Ovarian Cancer
High-grade serous ovarian cancer (HGSOC) is the most aggressive histological type of epithelial ovarian cancer, which is characterized by a high frequency of somatic TP53 mutations. We performed exome analyses of tumors and matched normal tissues of 34 Japanese patients with HGSOC and observed a sub...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4252108/ https://www.ncbi.nlm.nih.gov/pubmed/25460179 http://dx.doi.org/10.1371/journal.pone.0114491 |