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Molecular Characterization of an Intact p53 Pathway Subtype in High-Grade Serous Ovarian Cancer

High-grade serous ovarian cancer (HGSOC) is the most aggressive histological type of epithelial ovarian cancer, which is characterized by a high frequency of somatic TP53 mutations. We performed exome analyses of tumors and matched normal tissues of 34 Japanese patients with HGSOC and observed a sub...

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Detalles Bibliográficos
Autores principales: Hayano, Takahide, Yokota, Yuki, Hosomichi, Kazuyoshi, Nakaoka, Hirofumi, Yoshihara, Kosuke, Adachi, Sosuke, Kashima, Katsunori, Tsuda, Hitoshi, Moriya, Takuya, Tanaka, Kenichi, Enomoto, Takayuki, Inoue, Ituro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4252108/
https://www.ncbi.nlm.nih.gov/pubmed/25460179
http://dx.doi.org/10.1371/journal.pone.0114491