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Restriction Endonucleases from Invasive Neisseria gonorrhoeae Cause Double-Strand Breaks and Distort Mitosis in Epithelial Cells during Infection

The host epithelium is both a barrier against, and the target for microbial infections. Maintaining regulated cell growth ensures an intact protective layer towards microbial-induced cellular damage. Neisseria gonorrhoeae infections disrupt host cell cycle regulation machinery and the infection caus...

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Detalles Bibliográficos
Autores principales: Weyler, Linda, Engelbrecht, Mattias, Mata Forsberg, Manuel, Brehwens, Karl, Vare, Daniel, Vielfort, Katarina, Wojcik, Andrzej, Aro, Helena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4252111/
https://www.ncbi.nlm.nih.gov/pubmed/25460012
http://dx.doi.org/10.1371/journal.pone.0114208