Positive allosteric modulation of the adenosine A(2a) receptor attenuates inflammation

BACKGROUND: Adenosine is produced at high levels at inflamed sites as a by-product of cellular activation and breakdown. Adenosine mediates its anti-inflammatory activity primarily through the adenosine A(2a) receptor (A(2a)R), a member of the G-protein coupled receptors. A(2a)R agonists have demons...

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Detalles Bibliográficos
Autores principales: Welihinda, Ajith A, Amento, Edward P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253011/
https://www.ncbi.nlm.nih.gov/pubmed/25473378
http://dx.doi.org/10.1186/s12950-014-0037-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253011/
https://www.ncbi.nlm.nih.gov/pubmed/25473378
http://dx.doi.org/10.1186/s12950-014-0037-0

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