Evaluation of acid-labile S-protecting groups to prevent Cys racemization in Fmoc solid-phase peptide synthesis

Phosphonium and uronium salt-based reagents enable efficient and effective coupling reactions and are indispensable in peptide chemistry, especially in machine-assisted SPPS. However, after the activating and coupling steps with these reagents in the presence of tertiary amines, Fmoc derivatives of...

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Detalles Bibliográficos
Autores principales: Hibino, Hajime, Miki, Yasuyoshi, Nishiuchi, Yuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253322/
https://www.ncbi.nlm.nih.gov/pubmed/24357151
http://dx.doi.org/10.1002/psc.2585

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253322/
https://www.ncbi.nlm.nih.gov/pubmed/24357151
http://dx.doi.org/10.1002/psc.2585

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