Hypoxia-inducible factors enhance glutamate signaling in cancer cells

Signaling through glutamate receptors has been reported in human cancers, but the molecular mechanisms are not fully delineated. We report that in hepatocellular carcinoma and clear cell renal carcinoma cells, increased activity of hypoxia-inducible factors (HIFs) due to hypoxia or VHL loss-of-funct...

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Detalles Bibliográficos
Autores principales: Hu, Hongxia, Takano, Naoharu, Xiang, Lisha, Gilkes, Daniele M., Luo, Weibo, Semenza, Gregg L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253402/
https://www.ncbi.nlm.nih.gov/pubmed/25326682

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253402/
https://www.ncbi.nlm.nih.gov/pubmed/25326682

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