Plerixafor as a chemosensitizing agent in pediatric acute lymphoblastic leukemia: efficacy and potential mechanisms of resistance to CXCR4 inhibition

In spite of advances in the treatment of pediatric acute lymphoblastic leukemia (ALL), a significant number of children with ALL are not cured of their disease. We and others have shown that signaling from the bone marrow microenvironment confers therapeutic resistance, and that the interaction betw...

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Detalles Bibliográficos
Autores principales: Sison, Edward Allan R., Magoon, Daniel, Li, Li, Annesley, Colleen E., Rau, Rachel E., Small, Donald, Brown, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Clinical Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253409/
https://www.ncbi.nlm.nih.gov/pubmed/25333254

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253409/
https://www.ncbi.nlm.nih.gov/pubmed/25333254

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