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Glycogen synthase kinase-3β inhibition depletes the population of prostate cancer stem/progenitor-like cells and attenuates metastatic growth

Cancer cells with stem or progenitor properties play a pivotal role in the initiation, recurrence and metastatic potential of solid tumors, including those of the human prostate. Cancer stem cells are generally more resistant to conventional therapies thus requiring the characterization of key pathw...

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Detalles Bibliográficos
Autores principales: Kroon, Jan, in 't Veld, Lars S., Buijs, Jeroen T., Cheung, Henry, van der Horst, Geertje, van der Pluijm, Gabri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253412/
https://www.ncbi.nlm.nih.gov/pubmed/25344861