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Neutral competition of stem cells is skewed by proliferative changes downstream of Hh and Hpo
Neutral competition, an emerging feature of stem cell homeostasis, posits that individual stem cells can be lost and replaced by their neighbors stochastically, resulting in chance dominance of a clone at the niche. A single stem cell with an oncogenic mutation could bias this process and clonally s...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253521/ https://www.ncbi.nlm.nih.gov/pubmed/25092766 http://dx.doi.org/10.15252/embj.201387500 |