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Significant distinct branches of hierarchical trees: a framework for statistical analysis and applications to biological data

BACKGROUND: One of the most common goals of hierarchical clustering is finding those branches of a tree that form quantifiably distinct data subtypes. Achieving this goal in a statistically meaningful way requires (a) a measure of distinctness of a branch and (b) a test to determine the significance...

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Detalles Bibliográficos
Autores principales: Sun, Guoli, Krasnitz, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253613/
https://www.ncbi.nlm.nih.gov/pubmed/25409689
http://dx.doi.org/10.1186/1471-2164-15-1000