Functional chromatin features are associated with structural mutations in cancer

BACKGROUND: Structural mutations (SMs) play a major role in cancer development. In some cancers, such as breast and ovarian, DNA double-strand breaks (DSBs) occur more frequently in transcribed regions, while in other cancer types such as prostate, there is a consistent depletion of breakpoints in t...

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Detalles Bibliográficos
Autores principales: Grzeda, Krzysztof R, Royer-Bertrand, Beryl, Inaki, Koichiro, Kim, Hyunsoo, Hillmer, Axel M, Liu, Edison T, Chuang, Jeffrey H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253614/
https://www.ncbi.nlm.nih.gov/pubmed/25417144
http://dx.doi.org/10.1186/1471-2164-15-1013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253614/
https://www.ncbi.nlm.nih.gov/pubmed/25417144
http://dx.doi.org/10.1186/1471-2164-15-1013

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