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SNAP-25 is a promising novel cerebrospinal fluid biomarker for synapse degeneration in Alzheimer’s disease

BACKGROUND: Synaptic degeneration is an early pathogenic event in Alzheimer’s disease, associated with cognitive impairment and disease progression. Cerebrospinal fluid biomarkers reflecting synaptic integrity would be highly valuable tools to monitor synaptic degeneration directly in patients. We p...

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Detalles Bibliográficos
Autores principales: Brinkmalm, Ann, Brinkmalm, Gunnar, Honer, William G, Frölich, Lutz, Hausner, Lucrezia, Minthon, Lennart, Hansson, Oskar, Wallin, Anders, Zetterberg, Henrik, Blennow, Kaj, Öhrfelt, Annika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253625/
https://www.ncbi.nlm.nih.gov/pubmed/25418885
http://dx.doi.org/10.1186/1750-1326-9-53