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Alternate deacylating specificities of the archaeal sirtuins Sir2Af1 and Sir2Af2

Sirtuins were originally shown to regulate a wide array of biological processes such as transcription, genomic stability, and metabolism by catalyzing the NAD(+)-dependent deacetylation of lysine residues. Recent proteomic studies have revealed a much wider array of lysine acyl modifications in vivo...

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Detalles Bibliográficos
Autores principales: Ringel, Alison E, Roman, Christina, Wolberger, Cynthia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253809/
https://www.ncbi.nlm.nih.gov/pubmed/25200501
http://dx.doi.org/10.1002/pro.2546