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Alternate deacylating specificities of the archaeal sirtuins Sir2Af1 and Sir2Af2
Sirtuins were originally shown to regulate a wide array of biological processes such as transcription, genomic stability, and metabolism by catalyzing the NAD(+)-dependent deacetylation of lysine residues. Recent proteomic studies have revealed a much wider array of lysine acyl modifications in vivo...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253809/ https://www.ncbi.nlm.nih.gov/pubmed/25200501 http://dx.doi.org/10.1002/pro.2546 |