Multi-factor data normalization enables the detection of copy number aberrations in amplicon sequencing data

Motivation: Because of its low cost, amplicon sequencing, also known as ultra-deep targeted sequencing, is now becoming widely used in oncology for detection of actionable mutations, i.e. mutations influencing cell sensitivity to targeted therapies. Amplicon sequencing is based on the polymerase cha...

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Detalles Bibliográficos
Autores principales: Boeva, Valentina, Popova, Tatiana, Lienard, Maxime, Toffoli, Sebastien, Kamal, Maud, Le Tourneau, Christophe, Gentien, David, Servant, Nicolas, Gestraud, Pierre, Rio Frio, Thomas, Hupé, Philippe, Barillot, Emmanuel, Laes, Jean-François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Hitseq Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253825/
https://www.ncbi.nlm.nih.gov/pubmed/25016581
http://dx.doi.org/10.1093/bioinformatics/btu436

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253825/
https://www.ncbi.nlm.nih.gov/pubmed/25016581
http://dx.doi.org/10.1093/bioinformatics/btu436

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