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LoRDEC: accurate and efficient long read error correction

Motivation: PacBio single molecule real-time sequencing is a third-generation sequencing technique producing long reads, with comparatively lower throughput and higher error rate. Errors include numerous indels and complicate downstream analysis like mapping or de novo assembly. A hybrid strategy th...

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Detalles Bibliográficos
Autores principales: Salmela, Leena, Rivals, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253826/
https://www.ncbi.nlm.nih.gov/pubmed/25165095
http://dx.doi.org/10.1093/bioinformatics/btu538