Cargando…

Effects of Macromolecular Crowding on Amyloid Beta (16–22) Aggregation Using Coarse-Grained Simulations

[Image: see text] To examine the effect of crowding on protein aggregation, discontinuous molecular dynamics (DMD) simulations combined with an intermediate resolution protein model, PRIME20, were applied to a peptide/crowder system. The systems contained 192 Aβ(16–22) peptides and crowders of diame...

Descripción completa

Detalles Bibliográficos
Autores principales: Latshaw, David C., Cheon, Mookyung, Hall, Carol K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4254002/
https://www.ncbi.nlm.nih.gov/pubmed/25347801
http://dx.doi.org/10.1021/jp508970q