Cargando…
Constitutive activation of the ERK pathway in melanoma and skin melanocytes in Grey horses
BACKGROUND: Constitutive activation of the ERK pathway, occurring in the vast majority of melanocytic neoplasms, has a pivotal role in melanoma development. Different mechanisms underlie this activation in different tumour settings. The Grey phenotype in horses, caused by a 4.6 kb duplication in int...
Autores principales: | , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4254013/ https://www.ncbi.nlm.nih.gov/pubmed/25413220 http://dx.doi.org/10.1186/1471-2407-14-857 |