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Constitutive activation of the ERK pathway in melanoma and skin melanocytes in Grey horses
BACKGROUND: Constitutive activation of the ERK pathway, occurring in the vast majority of melanocytic neoplasms, has a pivotal role in melanoma development. Different mechanisms underlie this activation in different tumour settings. The Grey phenotype in horses, caused by a 4.6 kb duplication in int...
Autores principales: | Jiang, Lin, Campagne, Cécile, Sundström, Elisabeth, Sousa, Pedro, Imran, Saima, Seltenhammer, Monika, Pielberg, Gerli, Olsson, Mats J, Egidy, Giorgia, Andersson, Leif, Golovko, Anna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4254013/ https://www.ncbi.nlm.nih.gov/pubmed/25413220 http://dx.doi.org/10.1186/1471-2407-14-857 |
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