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Suppression of the hERG potassium channel response to premature stimulation by reduction in extracellular potassium concentration

Potassium channels encoded by human ether‐à‐go‐go‐related gene (hERG) mediate the cardiac rapid delayed rectifier K(+) current (I(Kr)), which participates in ventricular repolarization and has a protective role against unwanted premature stimuli late in repolarization and early in diastole. Ionic cu...

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Detalles Bibliográficos
Autores principales: Melgari, Dario, Du, Chunyun, El Harchi, Aziza, Zhang, Yihong, Hancox, Jules C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Periodicals, Inc. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4254092/
https://www.ncbi.nlm.nih.gov/pubmed/25318749
http://dx.doi.org/10.14814/phy2.12165