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Suppression of the hERG potassium channel response to premature stimulation by reduction in extracellular potassium concentration
Potassium channels encoded by human ether‐à‐go‐go‐related gene (hERG) mediate the cardiac rapid delayed rectifier K(+) current (I(Kr)), which participates in ventricular repolarization and has a protective role against unwanted premature stimuli late in repolarization and early in diastole. Ionic cu...
Autores principales: | Melgari, Dario, Du, Chunyun, El Harchi, Aziza, Zhang, Yihong, Hancox, Jules C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wiley Periodicals, Inc.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4254092/ https://www.ncbi.nlm.nih.gov/pubmed/25318749 http://dx.doi.org/10.14814/phy2.12165 |
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