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Suppression of histone deacetylation promotes the differentiation of human pluripotent stem cells towards neural progenitor cells

BACKGROUND: Emerging studies of human pluripotent stem cells (hPSCs) raise new prospects for neurodegenerative disease modeling and cell replacement therapies. Therefore, understanding the mechanisms underlying the commitment of neural progenitor cells (NPCs) is important for the application of hPSC...

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Detalles Bibliográficos
Autores principales: Yang, Juan, Tang, Yu, Liu, Hui, Guo, Fang, Ni, Jun, Le, Weidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4254204/
https://www.ncbi.nlm.nih.gov/pubmed/25406762
http://dx.doi.org/10.1186/s12915-014-0095-z