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Distance-based assessment of the localization of functional annotations in 3D genome reconstructions

BACKGROUND: Recent studies used the contact data or three-dimensional (3D) genome reconstructions from Hi-C (chromosome conformation capture with next-generation sequencing) to assess the co-localization of functional genomic annotations in the nucleus. These analyses dichotomized data point pairs b...

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Detalles Bibliográficos
Autores principales: Capurso, Daniel, Segal, Mark R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4254257/
https://www.ncbi.nlm.nih.gov/pubmed/25407917
http://dx.doi.org/10.1186/1471-2164-15-992