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Activation of mTOR Pathway in Myeloid-derived Suppressor Cells Stimulates Cancer Cell Proliferation and Metastasis in lal−/− Mice

Inflammation critically contributes to cancer metastasis, in which myeloid-derived suppressor cells (MDSCs) are an important participant. Although MDSCs are known to suppress immune surveillance, their roles in directly stimulating cancer cell proliferation and metastasis currently remain unclear. L...

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Detalles Bibliográficos
Autores principales: Zhao, Ting, Du, Hong, Ding, Xinchun, Walls, Katlin, Yan, Cong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4254377/
https://www.ncbi.nlm.nih.gov/pubmed/24882582
http://dx.doi.org/10.1038/onc.2014.143