Effects of Tumor Suppressor Lysyl Oxidase Propeptide on Prostate Cancer Xenograft Growth and Its Direct Interactions with DNA Repair Pathways

Lysyl oxidase (LOX) is a multifunctional protein required for normal collagen and elastin biosynthesis and maturation. In addition, LOX has complex roles in cancer in which the lysyl oxidase propeptide (LOX-PP) domain of secreted pro-LOX has tumor suppressor activity, while the active enzyme promote...

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Detalles Bibliográficos
Autores principales: Bais, Manish V., Ozdener, Gokhan Baris, Sonenshein, Gail E., Trackman, Philip C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4254378/
https://www.ncbi.nlm.nih.gov/pubmed/24882580
http://dx.doi.org/10.1038/onc.2014.147

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4254378/
https://www.ncbi.nlm.nih.gov/pubmed/24882580
http://dx.doi.org/10.1038/onc.2014.147

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