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Enhancer alterations in cancer: a source for a cell identity crisis

Enhancers are selectively utilized to orchestrate gene expression programs that first govern pluripotency and then proceed to highly specialized programs required for the process of cellular differentiation. Whereas gene-proximal promoters are typically active across numerous cell types, distal enha...

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Detalles Bibliográficos
Autores principales: Kron, Ken J, Bailey, Swneke D, Lupien, Mathieu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4254433/
https://www.ncbi.nlm.nih.gov/pubmed/25473436
http://dx.doi.org/10.1186/s13073-014-0077-3