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Enhancer alterations in cancer: a source for a cell identity crisis
Enhancers are selectively utilized to orchestrate gene expression programs that first govern pluripotency and then proceed to highly specialized programs required for the process of cellular differentiation. Whereas gene-proximal promoters are typically active across numerous cell types, distal enha...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4254433/ https://www.ncbi.nlm.nih.gov/pubmed/25473436 http://dx.doi.org/10.1186/s13073-014-0077-3 |