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Analysis of nascent RNA identifies a unified architecture of initiation regions at mammalian promoters and enhancers

Despite the conventional distinction between them, promoters and enhancers share many features in mammals, including divergent transcription and similar modes of transcription factor binding. Here, we examine the architecture of transcription initiation through comprehensive mapping of transcription...

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Detalles Bibliográficos
Autores principales: Core, Leighton J., Martins, André L., Danko, Charles G., Waters, Colin, Siepel, Adam, Lis, John T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4254663/
https://www.ncbi.nlm.nih.gov/pubmed/25383968
http://dx.doi.org/10.1038/ng.3142