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Nestin predicts a favorable prognosis in early ampullary adenocarcinoma and functions as a promoter of metastasis in advanced cancer

Nestin exhibits stemness characteristics and is over-expressed in several types of cancers. Downstream signaling of nestin [cyclin-dependent kinase 5 (CDK5) and Ras-related C3 botulinum toxin substrate 1 (Rac1)] functions in cancer to modulate cellular behaviors. We studied the function of nestin in...

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Detalles Bibliográficos
Autores principales: SHAN, YAN-SHEN, CHEN, YI-LING, LAI, MING-DERG, HSU, HUI-PING
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4254676/
https://www.ncbi.nlm.nih.gov/pubmed/25371063
http://dx.doi.org/10.3892/or.2014.3588