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Generation of a syngeneic orthotopic transplant model of prostate cancer metastasis

Progression to metastatic disease is the primary cause of mortality in men with prostate cancer (PCa). Mouse models which progress with spontaneous metastasis are limited. Such models would allow for extensive studies of molecular mechanisms of metastasis, and more definite pre- clinical therapy tri...

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Detalles Bibliográficos
Autores principales: Ellis, Leigh, Lehet, Kristin, Ku, ShengYu, Azabdaftari, Gissou, Pili, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4254774/
https://www.ncbi.nlm.nih.gov/pubmed/25485289