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Decreased plasma soluble erythropoietin receptor in high-altitude excessive erythrocytosis and Chronic Mountain Sickness

Excessive erythrocytosis (EE) is the hallmark of chronic mountain sickness (CMS), a prevalent syndrome in high-altitude Andean populations. Although hypoxemia represents its underlying stimulus, why some individuals develop EE despite having altitude-normal blood erythropoietin (Epo) concentration i...

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Detalles Bibliográficos
Autores principales: Villafuerte, Francisco C., Macarlupú, José Luis, Anza-Ramírez, Cecilia, Corrales-Melgar, Daniela, Vizcardo-Galindo, Gustavo, Corante, Noemí, León-Velarde, Fabiola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4254844/
https://www.ncbi.nlm.nih.gov/pubmed/25324511
http://dx.doi.org/10.1152/japplphysiol.00619.2014