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Whole Genome Transcript Profiling of Drug Induced Steatosis in Rats Reveals a Gene Signature Predictive of Outcome

Drug induced steatosis (DIS) is characterised by excess triglyceride accumulation in the form of lipid droplets (LD) in liver cells. To explore mechanisms underlying DIS we interrogated the publically available microarray data from the Japanese Toxicogenomics Project (TGP) to study comprehensively w...

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Detalles Bibliográficos
Autores principales: Sahini, Nishika, Selvaraj, Saravanakumar, Borlak, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4254931/
https://www.ncbi.nlm.nih.gov/pubmed/25470483
http://dx.doi.org/10.1371/journal.pone.0114085