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Antiviral Interferon-Beta Signaling Induced by Designed Transcription Activator-Like Effectors (TALE)
Here we show that designed transcription activator-like effectors (TALEs) that bind to defined areas of the interferon beta promoter are capable to induce IFN-beta expression and signaling in human cells. Importantly, TALE-mediated IFN-beta signaling occurs independently of pathogen pattern recognit...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255017/ https://www.ncbi.nlm.nih.gov/pubmed/25470486 http://dx.doi.org/10.1371/journal.pone.0114288 |