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Naturally Occurring Alpha-Synuclein Autoantibodies in Parkinson’s Disease: Sources of (Error) Variance in Biomarker Assays

Alpha-synuclein (α-Syn) plays a pivotal role in the pathophysiology of Parkinson’s disease (PD), which can partly be modulated by innate and adaptive immune functions, and vice versa. Here, naturally occurring α-Syn autoantibodies (α-Syn-nAbs) may be effective against α-Syn pathoetiology and may ser...

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Detalles Bibliográficos
Autores principales: Heinzel, Sebastian, Gold, Maike, Deuschle, Christian, Bernhard, Felix, Maetzler, Walter, Berg, Daniela, Dodel, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255021/
https://www.ncbi.nlm.nih.gov/pubmed/25470145
http://dx.doi.org/10.1371/journal.pone.0114566