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GAIP Interacting Protein C-Terminus Regulates Autophagy and Exosome Biogenesis of Pancreatic Cancer through Metabolic Pathways

GAIP interacting protein C terminus (GIPC) is known to play an important role in a variety of physiological and disease states. In the present study, we have identified a novel role for GIPC as a master regulator of autophagy and the exocytotic pathways in cancer. We show that depletion of GIPC-indu...

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Detalles Bibliográficos
Autores principales: Bhattacharya, Santanu, Pal, Krishnendu, Sharma, Anil K., Dutta, Shamit K., Lau, Julie S., Yan, Irene K., Wang, Enfeng, Elkhanany, Ahmed, Alkharfy, Khalid M., Sanyal, Arunik, Patel, Tushar C., Chari, Suresh T., Spaller, Mark R., Mukhopadhyay, Debabrata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255029/
https://www.ncbi.nlm.nih.gov/pubmed/25469510
http://dx.doi.org/10.1371/journal.pone.0114409