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GAIP Interacting Protein C-Terminus Regulates Autophagy and Exosome Biogenesis of Pancreatic Cancer through Metabolic Pathways
GAIP interacting protein C terminus (GIPC) is known to play an important role in a variety of physiological and disease states. In the present study, we have identified a novel role for GIPC as a master regulator of autophagy and the exocytotic pathways in cancer. We show that depletion of GIPC-indu...
Autores principales: | Bhattacharya, Santanu, Pal, Krishnendu, Sharma, Anil K., Dutta, Shamit K., Lau, Julie S., Yan, Irene K., Wang, Enfeng, Elkhanany, Ahmed, Alkharfy, Khalid M., Sanyal, Arunik, Patel, Tushar C., Chari, Suresh T., Spaller, Mark R., Mukhopadhyay, Debabrata |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255029/ https://www.ncbi.nlm.nih.gov/pubmed/25469510 http://dx.doi.org/10.1371/journal.pone.0114409 |
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