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SILAC-Based Quantitative Proteomic Analysis of Human Lung Cell Response to Copper Oxide Nanoparticles

Copper (II) oxide (CuO) nanoparticles (NP) are widely used in industry and medicine. In our study we evaluated the response of BEAS-2B human lung cells to CuO NP, using Stable isotope labeling by amino acids in cell culture (SILAC)-based proteomics and phosphoproteomics. Pathway modeling of the prot...

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Detalles Bibliográficos
Autores principales: Edelmann, Mariola J., Shack, Leslie A., Naske, Caitlin D., Walters, Keisha B., Nanduri, Bindu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255034/
https://www.ncbi.nlm.nih.gov/pubmed/25470785
http://dx.doi.org/10.1371/journal.pone.0114390