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Impact of Global Fxr Deficiency on Experimental Acute Pancreatitis and Genetic Variation in the FXR Locus in Human Acute Pancreatitis

BACKGROUND: Infectious complications often occur in acute pancreatitis, related to impaired intestinal barrier function, with prolonged disease course and even mortality as a result. The bile salt nuclear receptor farnesoid X receptor (FXR), which is expressed in the ileum, liver and other organs in...

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Detalles Bibliográficos
Autores principales: Nijmeijer, Rian M., Schaap, Frank G., Smits, Alexander J. J., Kremer, Andreas E., Akkermans, Louis M. A., Kroese, Alfons B. A., Rijkers, Ger. T., Schipper, Marguerite E. I., Verheem, André, Wijmenga, Cisca, Gooszen, Hein G., van Erpecum, Karel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255038/
https://www.ncbi.nlm.nih.gov/pubmed/25470824
http://dx.doi.org/10.1371/journal.pone.0114393