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Estrogen Induces Global Reorganization of Chromatin Structure in Human Breast Cancer Cells
In the cell nucleus, each chromosome is confined to a chromosome territory. This spatial organization of chromosomes plays a crucial role in gene regulation and genome stability. An additional level of organization has been discovered at the chromosome scale: the spatial segregation into open and cl...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255042/ https://www.ncbi.nlm.nih.gov/pubmed/25470140 http://dx.doi.org/10.1371/journal.pone.0113354 |