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Estrogen Induces Global Reorganization of Chromatin Structure in Human Breast Cancer Cells

In the cell nucleus, each chromosome is confined to a chromosome territory. This spatial organization of chromosomes plays a crucial role in gene regulation and genome stability. An additional level of organization has been discovered at the chromosome scale: the spatial segregation into open and cl...

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Detalles Bibliográficos
Autores principales: Mourad, Raphaël, Hsu, Pei-Yin, Juan, Liran, Shen, Changyu, Koneru, Prasad, Lin, Hai, Liu, Yunlong, Nephew, Kenneth, Huang, Tim H., Li, Lang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255042/
https://www.ncbi.nlm.nih.gov/pubmed/25470140
http://dx.doi.org/10.1371/journal.pone.0113354