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Apolipoprotein E in Synaptic Plasticity and Alzheimer’s Disease: Potential Cellular and Molecular Mechanisms

Alzheimer’s disease (AD) is clinically characterized with progressive memory loss and cognitive decline. Synaptic dysfunction is an early pathological feature that occurs prior to neurodegeneration and memory dysfunction. Mounting evidence suggests that aggregation of amyloid-β (Aβ) and hyperphospho...

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Detalles Bibliográficos
Autores principales: Kim, Jaekwang, Yoon, Hyejin, Basak, Jacob, Kim, Jungsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255096/
https://www.ncbi.nlm.nih.gov/pubmed/25358504
http://dx.doi.org/10.14348/molcells.2014.0248