Sevoflurane Postconditioning Protects Rat Hearts against Ischemia-Reperfusion Injury via the Activation of PI3K/AKT/mTOR Signaling

Phosphatidylinositol 3-kinase (PI3K)/protein kinase B (AKT) pathway plays a key role in myocardial ischemia-reperfusion (I/R) injury. Mammalian target of rapamycin (mTOR), a downstream target of PI3K/AKT signaling, is necessary and sufficient to protect the heart from I/R injury. Inhaled anesthetic...

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Detalles Bibliográficos
Autores principales: Zhang, Jing, Wang, Chen, Yu, Shuchun, Luo, Zhenzhong, Chen, Yong, Liu, Qin, Hua, Fuzhou, Xu, Guohai, Yu, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255182/
https://www.ncbi.nlm.nih.gov/pubmed/25471136
http://dx.doi.org/10.1038/srep07317

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255182/
https://www.ncbi.nlm.nih.gov/pubmed/25471136
http://dx.doi.org/10.1038/srep07317

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