Crosstalking noncoding RNAs contribute to cell-specific neurodegeneration in SCA7

What causes the tissue-specific pathology of diseases resulting from mutations in housekeeping genes? Specifically, in Spinocerebellar ataxia type 7 (SCA7), a neurodegenerative disorder caused by a CAG repeat expansion in ATXN7- an essential component of the mammalian transcription co-activation com...

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Detalles Bibliográficos
Autores principales: Tan, Jennifer Y., Vance, Keith W., Varela, Miguel A., Sirey, Tamara, Watson, Lauren M., Curtis, Helen J., Marinello, Martina, Alves, Sandro, Steinkraus, Bruno, Cooper, Sarah, Nesterova, Tatyana, Brockdorff, Neil, Fulga, Tudor, Brice, Alexis, Sittler, Annie, Oliver, Peter L., Wood, Matthew J., Ponting, Chris P., Marques, Ana C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255225/
https://www.ncbi.nlm.nih.gov/pubmed/25306109
http://dx.doi.org/10.1038/nsmb.2902

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255225/
https://www.ncbi.nlm.nih.gov/pubmed/25306109
http://dx.doi.org/10.1038/nsmb.2902

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