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Leptin-inhibited PBN neurons enhance counter-regulatory responses to hypoglycemia in negative energy balance

Hypoglycemia initiates the counter regulatory response (CRR), in which the sympathetic nervous system, glucagon, and glucocorticoids restore glucose to appropriate concentrations. During starvation, low leptin restrains energy utilization, enhancing long-term survival. To ensure short-term survival...

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Detalles Bibliográficos
Autores principales: Flak, Jonathan N., Patterson, Christa M., Garfield, Alastair S., D’Agostino, Giuseppe, Goforth, Paulette B., Sutton, Amy K., Malec, Paige A., Wong, Jenny-Marie T., Germani, Mark, Jones, Justin C., Rajala, Michael, Satin, Leslie, Rhodes, Christopher J., Olson, David P., Kennedy, Robert T., Heisler, Lora K., Myers, Martin G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255234/
https://www.ncbi.nlm.nih.gov/pubmed/25383904
http://dx.doi.org/10.1038/nn.3861