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The substrate specificity, enantioselectivity and structure of the (R)-selective amine : pyruvate transaminase from Nectria haematococca

During the last decade the use of transaminases for the production of pharmaceutical and fine chemical intermediates has attracted a great deal of attention. Transaminases are versatile biocatalysts for the efficient production of amine intermediates and many have (S)-enantiospecificity. Transaminas...

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Detalles Bibliográficos
Autores principales: Sayer, Christopher, Martinez-Torres, Ruben J, Richter, Nina, Isupov, Michail N, Hailes, Helen C, Littlechild, Jennifer A, Ward, John M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255305/
https://www.ncbi.nlm.nih.gov/pubmed/24618038
http://dx.doi.org/10.1111/febs.12778